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Hormonal fluctuations can alter collagen synthesis and ligament laxity, while muscle imbalances and poor neuromuscular control can compromise joint stability

However, abnormal desensitization of insulin signaling has been observed in the brain tissue of patients with AD even in the absence of DM ( Multiple parallels between impaired brain insulin signaling in AD and insulin resistance in T2DM have been reported

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Relaxing Warm Massage: A gentle heating effect enhances circulation and skin comfort