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Studies show that stopping GLP-1 therapy can lead to weight regain, which is why we focus on sustainable lifestyle changes alongside medication

Glutathione system in animal model of solid tumors: from regulation to therapeutic target

Of note, the effects of chronic activation or inhibition of POMC neurons differ between sexes, since female mice show resilience to chemogenetic manipulations of ARC POMC neurons despite similar electrophysiological changes under stress [151]

Flachs, P

When plasma glucose levels are low, GLP-1RAs do not stimulate insulin secretion, which helps to maintain glycemic control while also reducing the risk of hypoglycemia [3, 4]