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[50] [51] The motif is named after Michael Rossmann, who was the first scientist to notice how common this structure is within nucleotide-binding proteins

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Changes in gene expression levels of glutamate-cysteine ligase (GCL), glutathione peroxidase (GPx1), glutathione reductase (GR) and glutathione synthetase (GS) genes were analyzed by real-time qPCR on ABI PRISM 7500 (Applied Biosystems)

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To exclude a generalized antioxidant effect and establish pathway specificity, we compared mitoTEMPO with NAC, a broad-spectrum intracellular antioxidant

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