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For instance, compounds such as curcumin, resveratrol, and epigallocatechin gallate have been investigated in Phase I and Phase II studies for indications including cancer, metabolic disorders, and inflammatory diseases
Toxic freshwater cyanobacteria are very common worldwide and have been responsible for animal [156,157] and human intoxications [158,159] due to the heptapeptide hepatotoxins called microcystins as well as pentapeptide hepatotoxins called nodularins
Additionally, the peptide stability profile may differ in saline solutions
Preclinical research is an important part of the development of treatments, however results may be very different in clinical trials
These include proton pump inhibitors and H2 blockers, which are used to treat acid reflux or heartburn, and metformin, a diabetes medication