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There is a lack of randomised controlled trials tracking wider longevity outcomes for red light therapy

FIGURE 2 Lung cancer SLC7A11, highly expressed in NSCLC, is a potential target for ferroptosis ( in vivo and in vitro by mediating cellular uptake of cysteine and reducing ROS production

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additionally NAD + can be generated in the mitochondria from NMNAT3 80 , whose activity has been shown to be required in cells 77 , but dispensable in vivo as NAD + can be replenished through other pathways such as import from the cytosol 81