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Throughout, it is worth holding two ideas at once that the mechanistic story is genuinely rich and internally coherent, and that coherence is not the same as proof of a systemic effect in a living human being

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The main related signaling pathways and transformation factors are summarized as follows: NF-B, MAPK signaling pathway, JAK2/STAT3 signaling pathway, PI3K/Akt signaling pathway, AP-1, Nrf2, SIRT1, and HIF-1