do vitamin b12 injections have side effects Sublingual vs. B12 Injections: Which Option Is Right for You? – WhyNotNatural What Does a B12 Shot

Obese individuals often exhibit both elevated NNMT in adipose tissue and impaired muscle regenerative capacity a connection that NNMTs dual tissue effects could help explain

The study, conducted on 976 participants, showed that vitamin B12 levels were significantly lower in people who were obese and overweight (9)

Then, the doctor does blood tests to confirm B12 deficiency

Researchers studying NAD+ biology or methyl-donor pools should evaluate primary sources directly and note that NNMT inhibition has distinct mechanistic implications compared to direct NAD+ precursor supplementation with molecules like NMN or NAD+ itself

Treating hypocobalaminemia (B12 deficiency)

We will talk more about why that makes no sense at all below but you should be aware here that serum B12 testing is very inaccurate and shouldnt be used to guide dosing