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du Preez, H
The contemporary view is that IGFs serve dominant roles in cell proliferation, survival and organismal growth, whereas insulins primary functions include the regulation of fuel accumulation, storage and energy expenditure
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At this point, it is important to note that although there seems to be a trend suggesting a correlation between the number of interactions in the GST-GSH complexes and their affinity (Fig 6B), this is still an approximation that requires further analysis with more accurate computational methods to determine binding free energies
All peroxide incubation experiments included an untreated control group (mock-treated with DMSO for 9 h), as well as controls for complete oxidation (1 mM DIAM for 5 min) and complete reduction (10 mM DTT for 5 min)