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Since the predictive value of both the NAFLD Fibrosis Score and Fibrosis 4 Index is known to decline outside the age range 3565 years, agestratified thresholds for both markers were also applied according to the algorithm of McPherson et al.32 Subjects aged 35 years or less were not classified under either score

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The aim of this prespecified analysis was to evaluate the impact of semaglutide on liver enzymes and suspected MASLD in patients from the SELECT trial, and to explore the CV benefits of semaglutide in a subgroup at risk for substantial fibrosis as defined by FIB-4

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If dosage frequency is a concern, there are once-weekly options to choose from