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Ekta Kapoor, associate Professor of Medicine at Mayo Clinic, writes women with a greater self-reported menopause symptom burden had higher cortisol levels, signifying greater physiological stress. This keeps women alert at night, contributing to longer stretches of wakefulness, non-restorative rest, a buildup of sleep debt and the lower quality of life that comes with extreme fatigue, in general

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10.1038/cddis.2012.176 214 Tamargo-GmezI.MarioG