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The original authors interpreted the carry-over as evidence of programming a chronobiological system

Curtis L, Humayun MA, Walker J, Hampton K, Partridge H

It exhibits anti-inflammatory effects that help reduce swelling and pain, aiding in quicker and more comfortable recovery

In patients with hypersensitivity to insulin degludec or any of the excipients in TRESIBA [see WARNINGS AND PRECAUTIONS ]

doi: 10.1024/0036-7281/a000138