While their glucose-lowering effects are well documented, increasing evidence supports their role in modulating body composition, particularly in promoting fat mass loss while preserving lean muscle mass
In the STEP 1 trial, nausea, diarrhoea, vomiting or constipation affected around 74% of people on semaglutide, compared with about 48% on placebo, and a small number stopped treatment because of side effects
Tirzepatide, by contrast, activates both GLP-1 and GIP receptors simultaneously, creating a dual-hormone effect that amplifies metabolic responses in multiple pathways
As the industry pivots toward integrated solutions for obesity, fatty-liver and cardiometabolic disease, manufacturing, supply-chain sophistication and regulatory execution will become critical differentiators
22 Together, they're a heart-healthy power duo that protects your cardiovascular system
Commonly Observed Adverse Events Patients should be informed of the commonly-observed adverse events associated with the use of ORLISTAT which include oily spotting, flatus with discharge, fecal urgency, fatty/oily stool, oily evacuation, increased defecation, fecal incontinence [see Adverse Reactions (6.1)]
