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Author contributions Frances Chung conceived the study and wrote the study protocol

Immunoblot analysis of oxidized and glutathionylated proteins To measure the level of nuclear protein oxidation 10 g of nuclear lysates were derivatized, and the western blotting was performed according to the recommendation of the manufacturer

Discarding the upper plasma, wash with three times volume of PBS for 3 times (re-suspend blood cell with PBS, centrifuge at 600 g for 10 minutes), add equal volume of Reagent I

The literature review has confirmed that both Semaglutide and Zepbound are well-suited to be used as weight reducing agents

When to contact your provider: Most first-week side effects are mild and manageable