Age-related factors Older people are at more risk because with age the production of stomach acid and intrinsic factor (a protein necessary for B12 absorption) can decrease
Neelakantan H, Vance V, Wetzel MD, Wang HY, McHardy SF, Finnerty CC, Hommel JD, Watowich SJ. Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high-fat diet-induced obesity in mice. Biochem Pharmacol. 2018 Jul;154:161-171. doi: 10.1016/j.bcp.2018.05.003. Epub 2018 May 5. PMID: 29738706; PMCID: PMC6015571
It also has FDA approval
CJC-1295 At a glance, CJC-1295 seems like an all-around longevity-supporting peptide, touting better sleep, increased muscle mass and weight loss, boosted cognitive and immune function, and slowed skin aging (12, 13, 14) in animal studies
Current supplementation protocol calls for repeated parenteral injections of hydroxycobalamin over 6 weeks bypassing the diseased tissue
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