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Certain branded formulations of semaglutide such as Wegovy are FDA-approved for the treatment of obesity and chronic weight management

In 2024 and 2025, an increasing number of cases of ischemic optic neuropathy have been reported through the FDA adverse events reporting system (FAERS) for semaglutide drugs

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Marso SP, Daniels GH, Poulter NR, et al

In the STEP 1 trial published in the New England Journal of Medicine, participants received counseling on caloric restriction and physical activity recommendations, though no formal exercise program was required

GLP-1 receptor agonists are a class of medications that work by mimicking the bodys natural glucagon-like peptide-1 hormone