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doi: 10.3389/fnagi.2016.00108 244 GejlMBrockBEgefjordLVangKRungbyJGjeddeA

Cells were seeded into specialized 96-well plates at a density of 10 4 cells/well and allowed to adhere overnight

The FDA-approved prescribing information for both Ozempic and Wegovy does not list testosterone reduction as a known adverse effect, and the medication does not act on androgen receptors or directly inhibit testosterone synthesis pathways

Translational psychiatry

The study also reported that the miR-22 inhibition via the use of its anti-sense antagonist enhanced the expression of estrogen receptor 1 and SP1 transcription factor [68]