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Interestingly, the addition of hGSTs results in major changes in the regioselectivity of GSH conjugation of the reactive clozapine metabolite, possibly due to the different active site geometries of hGSTs [33]

C.Trujillo-EstradaL.LaFerlaF

Cells 11(21):3371 Franklin CC, Backos DS, Mohar I, White CC, Forman HJ, Kavanagh TJ (2009) Structure, function, and post-translational regulation of the catalytic and modifier subunits of glutamate cysteine ligase

2012 Dec;1826(2):443-57

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The test method must be suitable for its intended purpose