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PMID: 11 U.S

There is no overlap in clinical use

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However, an imbalance in the generation and elimination of reactive oxygen species (ROS) negatively affects sperm quality due to oxidative damage ( The role of OS in the etiology of male infertility has been the primary focus of our Stellenbosch University Reproductive Research Group (SURRG) over the last 10 years

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Astrocytes play a central role in maintaining CNS homeostasis through purinergic signaling, wherein extracellular ATP and its degradation product adenosine modulate synaptic activity, inflammation, and neuronal excitability via purinergic P2X, P2Y, and adenosine receptors [324, 326]