Consistent with this, the depletion of butyrate-producing bacteria and the concomitant reduction in intestinal butyrate levels reported in IBD patients compared with healthy individuals have highlighted the immunomodulatory role of this microbial metabolite (91, 100102)
Grndemann D, Schmig E
It's especially beneficial for individuals with coexisting conditions like type 2 diabetes or high blood pressure
10.1167/iovs.06-0038 38 GonzalezJ
However, it is worth noting that they are not medically approved in most places, and information about them usually comes from online forums and user reviews rather than clinical studies
Benefits of incretin mimetics By increasing insulin secretion and inhibiting glucagon release, incretin mimetics have blood glucose-lowering effects which help to reduce your HbA1c They have also been shown in clinical research studies to be beneficial in losing weight, compared with a placebo, when used in combination with diet and exercise Side effects Possible side effects of incretin mimetics include: Diarrhoea Nausea Vomiting Headaches Dizziness Increased sweating Indigestion Constipation Loss of appetite GLP1s in the news Due to the approval of semaglutide in the UK in 2023, there has been a surge in popularity of GLP1 drugs and research on the drug class.