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Just as Uber and Lyft set out to disrupt the taxi industry and Amazon changed how we think about shopping, many smaller but quickly growing companies are disrupting traditional models of health care

Constipation can be managed with osmotic laxatives (macrogol) or stimulant laxatives if needed

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FDA prescribing information, Mounjaro (tirzepatide) injection, BLA 215866: approved indications, once-weekly 2.515 mg titration, ~5-day half-life, boxed warning for thyroid C-cell tumors

According to our sensitivity analysis, the maximum weekly drug dose would expand to 10 mg/week if the oral bioavailability was increased by 10 fold or the manufacturing cost was reduced by 10 fold

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