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Nrf2 mediates the DNA methylation level of RANKL promoter by regulating the activity of DNA methyltransferase 3a, participating in the regulation of ferroptosis in osteoclasts and bone homeostasis

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Treatment Upon admission, treatment was initiated with an intravenous infusion of 0,9% saline with potassium, as well as continuous intravenous insulin, in accordance with the DKA management protocol of the Polish Diabetes Association ( 2 6.8 mmHg, HCO 3 - 6.6 mmol/l, BE -27.1 mmol/l

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