Start low and recheck labs or symptoms early
Patients report symptoms such as severe and prolonged vomiting, nausea, abdominal pain, and malnutrition
Direct sensing of dietary -6 linoleic acid through FABP5-mTORC1 signaling
Mechanistically, GLP-1RAs inhibit the activation of hepatic stellate cells (HSCs), which are the principal fibrogenic cell type in the liver
Clark RL, Robertson RT, Peter CP, Bland JA, Nolan TE, Oppenheimer L, et al
the guidelines recommend checking for usage of GLP-1-based agents prior to an elective procedure, informing the patient of the benefits and risks of these agents, dietary modifications and fasting in the preceding 24 hours (including 24 hours of clear fluids prior and 6 hours of standard fasting) to reduce the risk of aspiration