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The common feature of these pathways is that they can all be activated by inflammation, oxidative stress or mechanical injury and ultimately promote the activation of myofibroblasts, excessive deposition of extracellular matrix (ECM), and inhibit its degradation (Figure 1)

J Clin Gastroenterol (1997) 25 Suppl 1:S17985

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Doing so may cause accidents due to misuse or deterioration of quality

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First Week: Initial Response Some users notice subtle changes within the first three to seven days