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Differential diagnosis: Cholangiofibrosiscentral portions become atrophic, collagenized, and avascular whereas the actively proliferating portion is at the periphery

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According to the above kinetic data, the Michaelis-Menten parameter was calculated:Here V is the original velocity, and [S] is the concentration of TMB, V max is the maximum reaction velocity and K m is the Michaelis-Menten constant