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Nat Rev Drug Discov 14 , 781803 (2015)

Some factors that can affect skin pH include air pollution, sweat, acne, antibacterial products, sebum/skin moisture, and change in humidity levels according to the season

Lapatinib Suppresses Ferroptosis in KA-Induced Epileptic Mice To further investigate the potential molecular mechanism by which lapatinib exerted neuroprotection, the alterations of ferroptosis-related indices including 4-HNE (a common by-product of lipid peroxidation) (Figures 3A,B, KA injection resulted in the upregulation of 4-HNE levels and this phenomenon was reversed after pretreatment with lapatinib and Fer-1 (ANOVA, F (5,24) = 5.219, p = 0.009)

doi: 10.3390/molecules23092401 138 WangPLiuYKangSYLyuCHanXHoTet al

Dadvand, H