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Serum limitation-induced organ culture model of keloids and apoptotic induction of FOXO4-DRI in situ The keloid tissues were cut into 4-mm diameter cylinders using a corneal trephine for organ culture and cultured in a DMEM containing 2% FBS for 10 days to construct the serum limitation-induced senescent organ culture model of keloid tissues

This indicates that other mechanisms are involved in the maintenance of intracellular cysteine pool in vivo allowing tumor growth

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In this study, both the GLP-1MK-801-treated mice and the calorie-restricted mice exhibited improved insulin sensitivity relative to the vehicle treatment and both monotherapy control groups (Extended Data Fig

investigated the effect of metformin on ovarian angiogenesis by constructing a dehydroepiandrosterone-induced PCOS rat model

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