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And in June 2026, the first dedicated diabetes Phase 3 trial (TRANSCEND-T2D-1) confirmed 16.8% weight loss alongside -2.0% HbA1c reduction in 537 type 2 diabetes patients

The new work is the first to suggest that this type of drug could have such a protective effect in people, says behavioral neuroscientist Patricia Sue Grigson of Penn State College of Medicine in Hershey

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(While Ozempic may be prescribed off-label for weight loss, its not specifically approved for it.) Studies of long-term use of Wegovy can give us an idea of how long you can take semaglutide for weight loss

Some may stop and maintain with intensive behavioral and metabolic support