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A prodrug nanoparticle synthesized by conjugating PD-L1Pep-2 with doxorubicin via cathepsin B-cleavable peptide linker (FRRG) inhibited tumor progression in the 4T1 mouse breast tumor model by inducing doxorubicin-mediated immunogenic cell death and blocking PD-L1 through PD-L1Pep-2 102

Jerome MS, Kuthethur R, Kabekkodu SP, Chakrabarty S (2022) Regulation of mitochondrial function by forkhead transcription factors

This substantial hepatic storage, unusual for a water-soluble vitamin, provides a buffer against deficiency

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Hydroxocobalamin is often preferred in the UK and is known as Cobalin-H or Neo-Cytamen when branded