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A 2021 randomized controlled trial demonstrated that exenatide, a GLP-1 receptor agonist, significantly slowed cognitive decline in patients with early-stage Parkinsons disease compared to a placebo group (Athauda et al., 2021)

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Rac-1 regulates nuclear factor of activated T cells (NFAT) C1 nuclear translocation in response to Fcepsilon receptor type 1 stimulation of mast cells