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3 Traditional applications of Bovis Calculus The traditional applications of BC can be traced back to Shennongs Herbal Classic (Wang and Xue, 2008)

This reveals the ability of selected fragments to drive site-specific engagement of a distinct subset of cysteines in the human proteome, whose functional significance could be validated via biochemical assays and structural modeling

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The N-terminus of the amylin peptide is predicted to form a loop, stabilized by a disulfide bond, that points out of the TM area, thereby tolerating N-terminal lipidation