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[5] [6] The FLOW trial with semaglutide demonstrated significant reductions in kidney outcomes in patients with type 2 diabetes and chronic kidney disease
Georgiou-Siafis SK, Tsiftsoglou AS
Glowy, Dewy, and Soft, Oh My
This occurs for the following reasons: Hydrochloric acid deficiency from stomach issues or use of over the counter or prescription acid blocking medications (PPIs, H2 blockers ) Pancreatic enzyme deficiency and bile acid issues Microbiota imbalance leading to gut wall dysfunction Inflammatory conditions of the digestive tract Lack of soluble fermentable fiber (legumes, cherries, garlic, onions) that support beneficial intestinal bacteria which produce short chain fatty acids like butyrate The key supplements for fatigue B12 best used in a sublingual (under the tongue) form 1000 ucg of methylcobalamin Folate as methyl tetrahydrafolate (MTHF) 1-2 mg B complex with methyl B12, folate, B6 as pyridoxal 5 phosphate 25-50mg Magnesium either chelate, glycinate, threonate or citrate, 400-600mg Zinc as picolinate 25-50mg EPA-DHA (omega 3 fish oil) 1to 3 grams L-carnitine, CoQ10, alpha lipoic acid as mitochondrial support (See below) Curcumin, ashwaghanda, adaptogenic herbs (see adrenal treatment) Mitochondrial Dysfunction: An Underlying Reason for Fatigue Fatigue, whether chronic or intermittent, often has a nutritional basis
The effect of obesity pharmacotherapy on body composition, including muscle mass
In particular, taking L-Carnitine with carbohydrates as noted earlier in this article may be the most beneficial
