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In summary, the glutamatergic GLP-1-producing neurons in the NTS are activated by multiple peripheral signals and regulate many aspects of feeding behavior

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BPC-157 in particular has been extensively investigated in rodent gastrointestinal models, with laboratory studies examining ulcer-healing endpoints, mucosal blood flow markers, and cytoprotective signaling in gut epithelial cell preparations

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They point to research done in rodents related to nicotine addiction