This INNspired article is sponsored by Lexaria Bioscience (NASDAQ:LEXX)
Methods: Two cohorts of participants 18 and older were recruited from the United States Hereditary Angioedema Association (US HAEA) with a documented history of HAE due to C1-inhibitor deficiency (HAE-C1-INH): Cohort 1, self-referred
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To validate this effect in mice, we performed hyperinsulinemic-euglycemic clamps in Dpp4 +/+ (wild-type, WT) and Dpp4 / (global Dpp4 deletion) mice fed a high-fat, high-cholesterol (HFHC) diet for 12 weeks
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(d) metabolic markers, including high density lipoprotein, low density lipoprotein (LDL), glycated hemoglobin A1c (HbA1c), and fasting blood glucose (FBG)