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30 Other studies hint at effects on telomere length and cellular senescence, 31 with one trial even suggesting partial reversal of two key biological aging markers in older adults

Hermann P, Gera I, Borbely J, Fejerdy P, Madlena M

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The follow-up pivotal trial (METAOD006 / OPTIONS) enrolled a larger cohort and failed to replicate statistically significant weight loss, which led Metabolic Pharmaceuticals to halt the formal drug development program in 2007