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Phase 2 data showing 24% body weight loss is in humans, not mice but Phase 3 scale and long-term safety data are still pending
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Semaglutide (Wegovy, Ozempic and Rybelsus): risk of Non-arteritic Anterior Ischemic Optic Neuropathy (NAION) GLP-1 receptor agonists and dual GLP-1/ GIP receptor agonists: strengthened warnings on acute pancreatitis, including necrotising and fatal cases MHRA urges public to avoid illegal online weight-loss medicines this New Year MHRA reminds healthcare professionals to advise patients of the side effects of GLP-1 agonists and to report misuse MHRA finds evidence does not support a link between Glucagon-Like Peptide-1 (GLP-1) receptor agonists and suicidal and self-injurious thoughts and actions GLP-1 and dual GIP/GLP-1 receptor agonists: potential risk of pulmonary aspiration during general anaesthesia or deep sedation GLP-1 receptor agonists: reports of diabetic ketoacidosis when concomitant insulin was rapidly reduced or discontinued Anyone who suspects that theyve had an adverse reaction to a GLP-1 medicine, or who suspects it is not a genuine product, should report it to our Yellow Card scheme

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