For these patients, oral supplements may not be effective, and thats where B12 injections can make a difference
What SHBG Actually Does (And Why It Is
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This is particularly important if you are part of any of the groups considered to be at high risk of B12 deficiency, including alcoholics, smokers, those on diabetes drugs, adults over 65, those with gastrointestinal disorders and those who have had surgery relating to the digestive tract
The first, larger, outer capsule is coated with a special acid-resistant enteric coating, so when swallowed it bypasses the stomach and is resistant to its degrading factors such as digestive enzymes and stomach acids
10.1016/j.cis.2020.102165 124 LiuX.TangI.WainbergZ