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Nonetheless, these findings indicate that setmelanotide, while safe at approved doses, may have a limited therapeutic window at the higher doses necessary to treat general obesity

Pepinemab antibody blockade of SEMA4D in early Huntingtons disease: a randomized, placebo-controlled, phase 2 trial

Differences in assay methods preclude meaningful comparisons of the incidence of anti-drug antibodies in the studies described below with the incidence of anti-drug antibodies in other studies

The yeast cell assays were designed and conducted by JZ and BM

Resultsalong with the speed at which they occurvary between patients

At the bacterial genus level, Bacteroides was the taxa that was both dominant in abundance and had good discrimination between the two groups