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It will be exciting to see how this line of work evolves into better patient stratification, more rational drug selection, and ultimately more predictable therapeutic outcomes

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However, OCTN1 and OCTN2 both have narrower substrate specificity compared to polyspecific OCTs and OATs, and uptake assays performed with a large panel of drugs suggest that OCTN2 is not a general drug transporter 3,12,17,18