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These scenarios include differentiating idiopathic versus drug-induced autoimmune hepatitis (DI-AIH), cases with overlapping features of another liver pathology, or cases in which liver injury does not improve following medication withdrawal, suggesting an alternate diagnosis or delayed improvement
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Following a second administration of Donor+Cas9, plasma Exe4 levels increased and remained elevated for over 28 weeks, doubling the level of Exe4 production and secretion compared to a single administration, suggesting the potential for fine-tuning the regimen dose through repetitive administration (Supplementary Fig
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Within 24 to 48 hours : For others, it may take a day or two to notice a difference
doi: 10.1016/j.bbr.2014.11.003 143 MonroeS
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