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Most nausea resolves within the first few weeks

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On the metabolic side, the 2016 weight-loss meta-analysis by Pooyandjoo (PMID 27335245) pooled nine randomized trials (n = 911) using roughly 1.8-2 g/day and reported a mean weight difference of 1.33 kg versus control real but modest, and the analysis noted the effect shrank over time

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