As we age, oxidative stress, genetic factors, and stem cell exhaustion cause these melanocytes to reduce melanin output or disappear entirely
Because MOTS-c is a regulator of metabolic homeostasis that prevented high-fat diet (HFD)-induced obesity and insulin resistance 15 , we tested if MOTS-c also improved running performance under metabolic (dietary) stress
Every day, it's bombarded by things that damage it: UV radiation from the sun, pollution, stress, poor sleep, alcohol, and the natural metabolic processes your body runs just to keep you alive
Particularly concerning was the effect it had on the next generation
Mitochondria and cell death
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