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Patients whose only complaint is weight and who have no secondary concerns about skin, hair, inflammation, or tissue quality are better served by optimizing their GLP-1 protocol, adding resistance training, and addressing nutrition rather than adding a peptide that doesnt directly address their primary goal

Aronne et al., JAMA 2024 (SURMOUNT-4)

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En estudios experimentales de ERD el tratamiento con arGLP-1 se ha asociado con mejoras histolgicas (reduccin de la hipertrofia glomerular, de la expansin mesangial, del engrosamiento de la membrana basal glomerular y del dao tubulointersticial)110,111

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Bariatric surgery, lifestyle interventions and orlistat for severe obesity: the REBALANCE mixed-methods systematic review and economic evaluation