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The discussion highlighted the importance of vigilant monitoring of thyroid function tests, the adjustment of thyroid hormone replacement therapy, and the management of potential side effects

The critical pharmacological balance is that the GLP-1R activation offsets the hyperglycemic tendency of glucagon receptor agonism

After four weeks, the dose is usually increased to 0.5 mg weekly

But Ozempic may interact with insulin medications

Peer review Peer review information Nature Metabolism thanks Darleen Sandoval and the other, anonymous, reviewer(s) for their contribution to the peer review of this work

First, Ozempic use has not lowered cholesterol enough to effectively manage high cholesterol