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Safety Considerations for Non-Diabetics Taking Semaglutide Semaglutide is generally well-tolerated in non-diabetic individuals, though gastrointestinal side effects such as nausea, vomiting, and constipation occur in some users during the initial weeks

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A prominent example is Toxoplasma gondii infection, which, in animal models, alters behavior and increases the release of neurotransmitters such as dopamine, and the amount of dopamine release is correlated with the number of infected cells (32)

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GLP-1Rs is present in many tissues, suggesting that their widespread physiological functions beyond glycemic control could potentially include, for example, neuroprotective, anti-inflammatory, and cardioprotective activity [13]

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