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These studies underscore the paradoxical role of arginine metabolism and availability depending on the circumstances (e.g., immune cells infiltration and the type of arginine metabolizing enzymes expressed in these cells in the TME) and type of tumor, implying that arginine supplementation might be interesting for some, but not other tumors (Table 3)

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Researchers should verify kit performance in their specific sample matrix, as components in cell lysates or tissue homogenates can interfere with colorimetric reactions

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