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American Association of Clinical Endocrinology (AACE): Clinical practice guidelines and expert consensus statements on the treatment of obesity and diabetes with new pharmacological agents

The UK and Netherlands studies utilized the same treatment intensification approach as the present study, whereby patients discontinued initial therapies after HbA1c exceeded 7.5%, but the US and Denmark studies applied a lifetime treatment duration for oral semaglutide and empagliflozin [14, 15, 48, 50]

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If uncertainty arises about dosing or timing, consulting a healthcare professional is always the safest approach

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