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Despite these differences at the ligand-binding level, the intracellular face of the orforglipron-activated receptor closely resembles the peptide-activated state

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Front Neurosci 14:603373 Funahashi Y, Ariza A, Emi R, Xu Y, Shan W, Suzuki K, Kozawa S, Ahammad RU, Wu M, Takano T, Yura Y, Kuroda K, Nagai T, Amano M, Yamada K, Kaibuchi K (2019) Phosphorylation of Npas4 by MAPK regulates reward-related gene expression and behaviors

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doi: 10.3390/ijms22158093 136 KumarH.GuleriaS.KimtaN.DhalariaR.NepovimovaE.DhanjalD