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Fibroblast-like synoviocyte (FLS) are the predominant cell types of synovial intima 5 and assure the structural and physiological integrity of diarthrodial joints, regulating the synovial fluid composition and the extracellular matrix of the joint lining 6
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doi: 10.1152/ajpgi.00361.2020 164
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This pathogenic process is further influenced by oxidative and endoplasmic reticulum stress, GM dysbiosis, disruptions in genetic and epigenetic regulation, mitochondrial dysfunction, as well as various environmental and dietary determinants [8]
They talked, among other things, about the impact of cutting thousands of jobs at federal health agencies and the high cost of some of the most popular prescription drugs
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