Riboflavin-specific transporters are found on the outer membrane of the mitochondria
While previous literature has documented the pharmacological effects of erianin (6,7), to the best of our knowledge, there is a lack of comprehensive reviews that bridge the gap between its molecular mechanisms and the pharmaceutical strategies required to overcome its physicochemical limitations
doi: 10.1016/j.cmet.2019.10.007 20 DokaEIdaTDagnellMAbikoYLuongNCBalogNet al
Tuy nhin, cc cht ny u trong mc an ton theo quy nh cht lng m phm
in vitro experiments showed that SGK1 knockdown alleviated erastin-induced downregulation of Slc7a11, GPX4, GSH, and GSSG, while reducing lipid peroxidation, iron accumulation, and mitochondrial damage upregulation, suggesting that SGK1 modulates ferroptosis processes through inflammatory pathways in CHD (44)
doi: 10.3390/ijms19072124 263 AbdouHSAtlasEHachRJ