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The study concluded that 1% lidocaine yielded longer-lasting local anesthesia and the depth of anesthesia was significantly higher 30 minutes after administration compared to diphenhydramine.

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"We simply do not have the human data to make confident recommendations about BPC-157 for GI healing," noted a 2022 editorial in Peptides reviewing the state of the field

While research has not definitively shown that creatine worsens kidney function in healthy individuals, data in those with established kidney disease remain limited